2013 May - Changes in Brain Tissue Oxygenation After Treatment of Diffuse Traumatic Brain Injury by Erythropoietin
Bouzat, Pierre; Millet, Anne; Boue, Yvonnick; Pernet-Gallay, Karin; Trouve-Buisson, Thibaut; Gaide-Chevronnay, Lucie; Barbier, Emmanuel L.; Payen, Jean-Francois; Critical Care Medicine. 41(5):1316-1324, May 2013.
Objectives: To investigate the effects of recombinant human erythropoietin on brain oxygenation in a model of diffuse traumatic brain injury.
2013 May - Renal Perfusion Assessment by Renal Doppler During Fluid Challenge in Sepsis
Schnell, David; Camous, Laurent; Guyomarc’h, Stéphane; Duranteau, Jacques; Canet, Emmanuel; Gery, Pierre; Dumenil, Anne-Sylvie; Zeni, Fabrice; Azoulay, Elie; Darmon, Michael; Critical Care Medicine. 41(5):1214-1220, May 2013.
Objectives: To assess renal resistive index variations in response to fluid challenge.
2013 May - Continuous Administration of Enteral Lipid- and Protein-Rich Nutrition Limits Inflammation in a Human Endotoxemia Model
Lubbers, Tim; Kox, Matthijs; de Haan, Jacco-Juri; Greve, Jan Willem; Pompe, Jan C.; Ramakers, Bart P.; Pickkers, Peter; Buurman, Wim A.; Critical Care Medicine. 41(5):1258-1265, May 2013.
Objective: An overzealous inflammatory response is an important cause of morbidity and mortality in surgical, trauma, and critically ill patients. Enteral administration of lipid-rich nutrition was previously shown to attenuate inflammation and reduce organ damage via a cholecystokinin-1 receptor–mediated vagovagal reflex in animal studies. The current preclinical study investigates the immunomodulatory potential of a custom-made enteral nutrition during systemic inflammation in man.
2013 May - Extracorporeal Cardiopulmonary Resuscitation for Patients With Out-of-Hospital Cardiac Arrest of Cardiac Origin: A Propensity-Matched Study and Predictor Analysis
Maekawa, Kunihiko; Tanno, Katsutoshi; Hase, Mamoru; Mori, Kazuhisa; Asai, Yasufumi; Critical Care Medicine. 41(5):1186-1196, May 2013.
Objective: Encouraging results of extracorporeal cardiopulmonary resuscitation for patients with refractory cardiac arrest have been shown. However, the independent impact on the neurologic outcome remains unknown in the out-of-hospital population. Our objective was to compare the neurologic outcome following extracorporeal cardiopulmonary resuscitation and conventional cardiopulmonary resuscitation and determine potential predictors that can identify candidates for extracorporeal cardiopulmonary resuscitation among patients with out-of-hospital cardiac arrest of cardiac origin.
2013 May - Fast-track failure after cardiac surgery: external model validation and implications to ICU bed utilization
Lee A, Zhu F, Underwood MJ, Gomersall CD.; Crit Care Med. 2013 May;41(5):1205-13.
OBJECTIVE: To facilitate the planning of perioperative care pathways, a fast-track failure prediction model has been developed in patients undergoing cardiac surgery. This study externally validated such a fast-track failure risk prediction model and determined the potential clinical consequences to ICU bed utilization.
2013 May - High-Osmolarity Saline in Neurocritical Care: Systematic Review and Meta-Analysis
Lazaridis, Christos; Neyens, Ron; Bodle, Jeffrey; DeSantis, Stacia M.; Critical Care Medicine. 41(5):1353-1360, May 2013.
Background and Purpose: Intracranial hypertension and cerebral edema are known contributors to secondary brain injury and to poor neurologic outcomes. Small volume solutions of exceedingly high osmolarity, such as 23.4% saline, have been used for the management of intracranial hypertension crises and as a measure to prevent or reverse acute brain tissue shifts. We conducted a systematic literature review on the use of 23.4% saline in neurocritically ill patients and a meta-analysis of the effect of 23.4% saline on intracranial pressure reduction.
2013 Apr - Continuous Electroencephalographic Monitoring in Critically Ill Patients: Indications, Limitations, and Strategies
Sutter, Raoul; Stevens, Robert D.; Kaplan, Peter W.; Critical Care Medicine. 41(4):1124-1132, April 2013
Objective: Continuous electroencephalography as a bedside monitor of cerebral activity has been used in a range of critically ill patients. This review compiles the indications, limitations, and strategies for continuous electroencephalography in the ICU.
2013 Apr - Prognosis in Severe Brain Injury
Stevens, Robert D.; Sutter, Raoul; Critical Care Medicine. 41(4):1104-1123, April 2013
Background: The prediction of neurologic outcome is a fundamental concern in the resuscitation of patients with severe brain injury.
2013 Apr - Acute Kidney Injury in the Critically Ill: Is Iodinated Contrast Medium Really Harmful?
Ehrmann, Stephan; Badin, Julie; Savath, Laurent; Pajot, Olivier; Garot, Denis; Pham, Tài; Capdevila, Xavier; Perrotin, Dominique; Lakhal, Karim; Critical Care Medicine. 41(4):1017-1026, April 2013
Objectives: To assess whether the use of iodinated contrast medium increases the incidence of acute kidney injury in ICU patients, compared with patients not receiving iodinated contrast medium.
2013 Apr - Fluid Resuscitation of Adults With Severe Falciparum Malaria: Effects on Acid-Base Status, Renal Function, and Extravascular Lung Water
Hanson, Josh P.; Lam, Sophia W.K.; Mohanty, Sanjib; Alam, Shamshul; Pattnaik, Rajyabardhan; Mahanta, Kishore C.; Hasan, Mahatab Uddin; Charunwatthana, Prakaykaew; Mishra, Saroj K.; Day, Nicholas P.J.; White, Nicholas J.; Dondorp, Arjen M.; Critical Care Medicine. 41(4):972-981, April 2013
Objective: To evaluate the efficacy and safety of liberal fluid resuscitation of adults with severe malaria.
2013 Apr - Pleural Effusion in Patients With Acute Lung Injury: A CT Scan Study
Chiumello, Davide; Marino, Antonella; Cressoni, Massimo; Mietto, Cristina; Berto, Virna; Gallazzi, Elisabetta; Chiurazzi, Chiara; Lazzerini, Marco; Cadringher, Paolo; Quintel, Michael; Gattinoni, Luciano; Critical Care Medicine. 41(4):935-944, April 2013
Objectives: Pleural effusion is a frequent finding in patients with acute respiratory distress syndrome. To assess the effects of pleural effusion in patients with acute lung injury on lung volume, respiratory mechanics, gas exchange, lung recruitability, and response to positive end-expiratory pressure.