2011 Feb - Clinical effectiveness and risk of emerging resistance associated with prolonged use of antibiotic-impregnated catheters: More than 0.5 million catheter days and 7 years of clinical experience
Ramos ER, Reitzel R, Jiang Y, Hachem RY, Chaftari AM, Chemaly RF, Hackett B, Pravinkumar SE, Nates J, Tarrand JJ, Raad II.; Crit Care Med. 2011 Feb;39(2):245-51.
OBJECTIVES: : Catheters coated with minocycline and rifampin are proven to decrease the rates of central line-associated bloodstream infection; however, it is unclear whether success occurs independent of other infection control precautions. We evaluated the effect of catheters coated with minocycline and rifampin with and without other infection control precautions on our rates of central line-associated bloodstream infection in critically ill patients and on antibiotic resistance throughout the hospital and in the intensive care unit.
2011 Jan - Severity of illness scoring systems in the intensive care unit [Review]
Keegan MT, Gajic O, Afessa B. ;Crit Care Med. 2011 Jan;39(1):163-9.
OBJECTIVE: : Adult intensive care unit prognostic models have been used for predicting patient outcome for three decades. The goal of this review is to describe the different versions of the main adult intensive care unit prognostic models and discuss their potential roles.
2011 Jan - Jejunal tube placement in critically ill patients: A prospective, randomized trial comparing the endoscopic technique with the electromagnetically visualized method
Holzinger U, Brunner R, Miehsler W, Herkner H, Kitzberger R, Fuhrmann V, Metnitz PG, Kamolz LP, Madl C.; Crit Care Med. 2011 Jan;39(1):73-7.
OBJECTIVE: : Head-to-head comparison of the success rate of jejunal placement of a new electromagnetically visualized jejunal tube with that of the endoscopic technique in critically ill patients.
2011 Jan - Antiarrhythmic drug therapy for sustained ventricular arrhythmias complicating acute myocardial infarction
Piccini JP, Schulte PJ, Pieper KS, Mehta RH, White HD, Van de Werf F, Ardissino D, Califf RM, Granger CB, Ohman EM, Alexander JH.; Crit Care Med. 2011 Jan;39(1):78-83
OBJECTIVE: : Few data exist to guide antiarrhythmic drug therapy for sustained ventricular tachycardia/ventricular fibrillation after acute myocardial infarction. The objective of this analysis was to describe the survival of patients with sustained ventricular tachycardia/ventricular fibrillation after myocardial infarction according to antiarrhythmic drug treatment.
2011 Jan - Take Heart America: A comprehensive, community-wide, systems-based approach to the treatment of cardiac arrest
Lick CJ, Aufderheide TP, Niskanen RA, Steinkamp JE, Davis SP, Nygaard SD, Bemenderfer KK, Gonzales L, Kalla JA, Wald SK, Gillquist DL, Sayre MR, Oski Holm SY, Oakes DA, Provo TA, Racht EM, Olsen JD, Yannopoulos D, Lurie KG.; Crit Care Med. 2011 Jan;39(1):26-33.
OBJECTIVES: To determine out-of-hospital cardiac arrest survival rates before and after implementation of the Take Heart America program (a community-based initiative that sequentially deployed all of the most highly recommended 2005 American Heart Association resuscitation guidelines in an effort to increase out-of-hospital cardiac arrest survival).
2010 Dec - A comparison of intravascular and surface cooling techniques in comatose cardiac arrest survivors
Tømte O, Drægni T, Mangschau A, Jacobsen D, Auestad B, Sunde K.; Crit Care Med. 2010 Dec 16. [Epub ahead of print]
OBJECTIVES: Mild therapeutic hypothermia after out-of-hospital cardiac arrest is usually achieved either by surface cooling or by core cooling via the patient's bloodstream. We compared modern core (Coolgard) and surface (Arctic Sun) cooling devices with a zero hypothesis of equal cooling, complications, and neurologic outcomes.
2010 Dec - Fasciculations in brain death
Beckmann YY, Ciftçi Y, Seçil Y, Eren S. ;Crit Care Med. 2010 Dec;38(12):2377-8.
OBJECTIVES: Brain death is the colloquial name for human death determined by tests showing irreversible cessation of the clinical functions of the brain. Spontaneous and reflex movements have been described in brain death. The aim of this report is to describe a brain-dead patient with unusual motor movements.
2010 Dec - Plasma adiponectin and mortality in critically ill subjects with acute respiratory failure
Walkey AJ, Rice TW, Konter J, Ouchi N, Shibata R, Walsh K, Deboisblanc BP, Summer R.; Crit Care Med. 2010 Dec;38(12):2329-2334.
OBJECTIVE: Adiponectin, an anti-inflammatory cytokine produced by adipose tissue, has been shown to modulate survival in animal models of critical illness. We examined the association between plasma adiponectin and clinical outcomes in critically ill patients with acute respiratory failure.
2010 Nov - Extracorporeal cardiopulmonary resuscitation in patients with inhospital cardiac arrest: A comparison with conventional cardiopulmonary resuscitation
Shin TG, Choi JH, Jo IJ, Sim MS, Song HG, Jeong YK, Song YB, Hahn JY, Choi SH, Gwon HC, Jeon ES, Sung K, Kim WS, Lee YT.; Crit Care Med. 2010 Nov 4. [Epub ahead of print]
OBJECTIVE: We investigated whether the survival of patients with inhospital cardiac arrest could be extended by extracorporeal cardiopulmonary resuscitation supported with extracorporeal membrane oxygenation compared with those of conventional cardiopulmonary resuscitation.
2010 Nov - High permeability dialysis membrane allows effective removal of myoglobin in acute kidney injury resulting from rhabdomyolysis
Sorrentino SA, Kielstein JT, Lukasz A, Sorrentino JN, Gohrbandt B, Haller H, Schmidt BM.; Crit Care Med. 2010 Nov 4. [Epub ahead of print]
OBJECTIVE: The objective of this study was to test the ability of myoglobin removal of a novel, high-permeability polysulphone dialyzer in acute kidney injury as a result of rhabdomyolysis.
2010 Oct - Comparison of norepinephrine-dobutamine to epinephrine for hemodynamics, lactate metabolism, and organ function variables in cardiogenic shock. A prospective, randomized pilot study
Levy B, Perez P, Perny J, Thivilier C, Gerard A.; Crit Care Med. 2010 Oct 28.
OBJECTIVE: There is no study that has compared, in a randomized manner, which vasopressor is most suitable in optimizing both systemic and regional hemodynamics in cardiogenic shock patients. Hence, the present study was designed to compare epinephrine and norepinephrine-dobutamine in dopamine-resistant cardiogenic shock.
2010 Oct - Jejunal tube placement in critically ill patients: A prospective, randomized trial comparing the endoscopic technique with the electromagnetically visualized method
Holzinger U, Brunner R, Miehsler W, Herkner H, Kitzberger R, Fuhrmann V, Metnitz PG, Kamolz LP, Madl C.;Crit Care Med. 2010 Oct 28.
OBJECTIVE: Head-to-head comparison of the success rate of jejunal placement of a new electromagnetically visualized jejunal tube with that of the endoscopic technique in critically ill patients.
2010 Nov - Procalcitonin-guided algorithms of antibiotic therapy in the intensive care unit: A systematic review and meta-analysis of randomized controlled trials
Kopterides P, Siempos II, Tsangaris I, Tsantes A, Armaganidis A.; Crit Care Med. 2010 Nov;38(11):2229-41.
OBJECTIVE: There is increasing interest for strategies that could curtail antibiotic resistance in the critical care setting. We sought to determine the effectiveness and safety of procalcitonin-guided algorithms in the management of septic patients in the intensive care unit.
2010 Nov- Stress ulcer prophylaxis in the new millennium: A systematic review and meta-analysis
Marik PE, Vasu T, Hirani A, Pachinburavan M.; Crit Care Med. 2010 Nov;38(11):2222-8.
BACKGROUND: Recent observational studies suggest that bleeding from stress ulceration is extremely uncommon in intensive care unit patients. Furthermore, the risk of bleeding may not be altered by the use of acid suppressive therapy. Early enteral tube feeding (initiated within 48 hrs of intensive care unit admission) may account for this observation. Stress ulcer prophylaxis may, however, increase the risk of hospital-acquired pneumonia and Clostridia difficile infection.
2010 Nov - Feasibility of physical and occupational therapy beginning from initiation of mechanical ventilation
Pohlman MC, Schweickert WD, Pohlman AS, Nigos C, Pawlik AJ, Esbrook CL, Spears L, Miller M, Franczyk M, Deprizio D, Schmidt GA, Bowman A, Barr R, McCallister K, Hall JB, Kress JP.; Crit Care Med. 2010 Nov;38(11):2089-94
Objective: Physical and occupational therapy are possible immediately after intubation in mechanically ventilated medical intensive care unit patients. The objective of this study was to describe a protocol of daily sedative interruption and early physical and occupational therapy and to specify details of intensive care unit-based therapy, including neurocognitive state, potential barriers, and adverse events related to this intervention.
2010 Sep - Common complications in the surgical intensive care unit [Review]
Sawyer RG, Leon CA. Crit Care Med. 2010 Sep;38(9 Suppl):S483-93.
Surgical and trauma intensive care units provide the facilities, resources, and personnel needed to care for patients who have been severely injured, present with acute surgical emergencies, require prolonged and complex elective surgical procedures, or have severe underlying medical conditions. Correcting the immediately evident physiologic derangement is only the first step in the care of these patients, because in many cases their prognosis and ultimate outcome will depend on whether additional insults accrued during their intensive care unit and hospital stay will prevent them from a full recovery.
2010 Sep - Alcohol withdrawal syndromes in the intensive care unit [Review]
Sarff M, Gold JA. Crit Care Med. 2010 Sep;38(9 Suppl):S494-501.
This article reviews the pathophysiology, diagnosis, and treatment of alcohol withdrawal syndromes in the intensive care unit as well as the literature on the optimal pharmacologic strategies for treatment of alcohol withdrawal syndromes in the critically ill.
2010 Oct - Clinical outcomes and prognostic factors for patients with Vibrio vulnificus infections requiring intensive care: a 10-yr retrospective study
Chen SC, Chan KS, Chao WN, Wang PH, Lin DB, Ueng KC, Kuo SH, Chen CC, Lee MC. Crit Care Med. 2010 Oct;38(10):1984-90
Objective: Vibrio vulnificus infection is uncommon but potentially life-threatening. The aim of this study was to evaluate clinical outcomes and prognostic factors for patients with V. vulnificus infections admitted to an intensive care unit.
2010 Oct - Constipation in long-term ventilated patients: Associated factors and impact on intensive care unit outcomes
Gacouin A, Camus C, Gros A, Isslame S, Marque S, Lavoué S, Chimot L, Donnio PY, Le Tulzo Y.; Crit Care Med. 2010 Oct;38(10):1933-8.
Objectives: To characterize the factors associated with delayed defecation in long-term ventilated patients and to examine the relationship between delayed defecation and logistic organ dysfunction scores, acquired bacterial infections, and mortality in the intensive care unit.

